...access to new pools of investors, the community opening their arms and wallets— all giving your business a shot to make it big. While crowdfunding (both donation and equity based) offers amazing opportunities, it also brings fiduciary responsibilities, commitments of time, reporting requirements and the potential to let down the people who mean...
Sunday 5 August 2012
What Is a Cutaway?
Filmmakers use a number of editing techniques in order to compress time or provide a visual break for the audience. One popular editing technique is known as a cutaway, primarily because it cuts away from the main action for a short time. A cutaway shot is not necessarily the same as a flashback or flash forward, in which the timeline of the film is moved backwards or...
What Is a Cutaway?
What Is a Cutaway?
Farm Software Tries to Make Its Mark - Digital Domain
Digital Domain: Farm Software Tries to Make Its Mark - Digital Domain
Cloud computing and other Internet services are coming to agriculture, allowing farmers to keep better track of their crops, livestock and expenses.
Fragile X, Down Syndrome Involve Similar Pathways
Fragile X, Down Syndrome Involve Similar Pathways:
Mental disabilities stemming from Fragile X and Down syndrome involve similar molecular pathways, according to a new study published in The EMBO Journal.
Both disorders are characterized by problems with the processes that regulate the way nerve cells develop dendritic spines—the small protrusions on the surface of nerve cells that are vital for communication in the brain.
“We have shown for the first time that some of the proteins altered in Fragile X and Down syndromes are common molecular triggers of intellectual disability in both disorders,” said Kyung-Tai Min, a professor at Indiana University and the Ulsan National Institute of Science and Technology in Korea.
“Specifically, two proteins interact with each other in a way that limits the formation of spines or protrusions on the surface of dendrites.”
“These outgrowths of the cell are essential for the formation of new contacts with other nerve cells and for the successful transmission of nerve signals. When the spines are impaired, information transfer is impeded and mental retardation takes hold,” he said.
Two of the most common genetic causes of intellectual disability are Fragile X and Down syndromes.
Fragile X syndrome is triggered by a single gene mutation that prevents the production of a protein needed for proper neural development (Fragile X mental retardation protein). For Down syndrome to occur, all or a part of a third copy of chromosome 21 must be present.
Although each syndrome is due to a separate genetic difference, the researchers identified a shared molecular pathway in mice that triggers intellectual disability in both disorders.
Down syndrome mice models have difficulties with memory and brain function, and the development of the heart is often compromised, symptoms that are also observed in humans with Down syndrome.
“We believe these experiments provide an important step forward in understanding the multiple roles of DSCR1 in neurons and in identifying a molecular interaction that is closely linked to intellectual disability for both syndromes,” said Min.
Source: The EMBO Journal
Source:Google Reader
Mental disabilities stemming from Fragile X and Down syndrome involve similar molecular pathways, according to a new study published in The EMBO Journal.
Both disorders are characterized by problems with the processes that regulate the way nerve cells develop dendritic spines—the small protrusions on the surface of nerve cells that are vital for communication in the brain.
“We have shown for the first time that some of the proteins altered in Fragile X and Down syndromes are common molecular triggers of intellectual disability in both disorders,” said Kyung-Tai Min, a professor at Indiana University and the Ulsan National Institute of Science and Technology in Korea.
“Specifically, two proteins interact with each other in a way that limits the formation of spines or protrusions on the surface of dendrites.”
“These outgrowths of the cell are essential for the formation of new contacts with other nerve cells and for the successful transmission of nerve signals. When the spines are impaired, information transfer is impeded and mental retardation takes hold,” he said.
Two of the most common genetic causes of intellectual disability are Fragile X and Down syndromes.
Fragile X syndrome is triggered by a single gene mutation that prevents the production of a protein needed for proper neural development (Fragile X mental retardation protein). For Down syndrome to occur, all or a part of a third copy of chromosome 21 must be present.
Although each syndrome is due to a separate genetic difference, the researchers identified a shared molecular pathway in mice that triggers intellectual disability in both disorders.
Down syndrome mice models have difficulties with memory and brain function, and the development of the heart is often compromised, symptoms that are also observed in humans with Down syndrome.
“We believe these experiments provide an important step forward in understanding the multiple roles of DSCR1 in neurons and in identifying a molecular interaction that is closely linked to intellectual disability for both syndromes,” said Min.
Source: The EMBO Journal
Source:Google Reader
Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99
Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99: Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99
Source:Google Reader
Source:Google Reader
Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99
Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99: Save $30 on HP Officejet e- All in One Printer 6700 Premium. $139.99
Source:Google Reader
Source:Google Reader
U.S. Drivers Fear Tech Distraction, Embrace Tech Anyway
U.S. Drivers Fear Tech Distraction, Embrace Tech Anyway: Three quarters of Americans fear that too much in-car connectivity, such as entertainment tech, can cause dangerous distraction, according to a survey of 2,634 U.S. adults aged 18 and older by polling firm Harris Interactive.
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This is Now Shows Real-Time Instagram Uploads
This is Now Shows Real-Time Instagram Uploads: The website showcases Instagram action in five busy cities, consolidating a kaleidoscope of images from around the world for quick perusal.
Source:Google Reader
Source:Google Reader
Whois Tools 1.0 (GPL)
Whois Tools 1.0 (GPL): A WHOIS and DNS lookup application for web designers and developers (read more)
Source:Google Reader
Source:Google Reader
Portable Webserver 1.4.1 Beta (Freeware)
Portable Webserver 1.4.1 Beta (Freeware): Useful and fast webserver (read more)
Source:Google Reader
Source:Google Reader
Pro Schedule Client Server 7.33 Build 7.330 (Trial)
Pro Schedule Client Server 7.33 Build 7.330 (Trial): Simple to use multi-user client/server application for booking appointments. (read more)
Source:Google Reader
Source:Google Reader
Yandex Mail Watcher 1.53 (GPL)
Yandex Mail Watcher 1.53 (GPL): Securely verify your Yandex email in Firefox (read more)
Source:Google Reader
Source:Google Reader
Web Developer Tool 1.0.1 (Freeware)
Web Developer Tool 1.0.1 (Freeware): Launch and close Apache and MySQL (read more)
Source:Google Reader
Source:Google Reader
Jazz-Plugin for Firefox 1.1 (BSD License)
Jazz-Plugin for Firefox 1.1 (BSD License): Low-level MIDI support for Firefox (read more)
Source:Google Reader
Source:Google Reader
GAC Manager 1.0 (MIT License)
GAC Manager 1.0 (MIT License): Global Assembly Cache management utility (read more)
Source:Google Reader
Source:Google Reader
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